The Systems Study
The SYSTEMS study was a clinical trial set up to test whether a standard dose of radiotherapy is helpful for pain in MPM. ‘SYSTEMS’ stands for ‘Symptoms Study of radiotherapy in Mesothelioma’. This study recruited 40 patients from 3 cancer centres over 18 months and gave a standard dose of radiotherapy over 1 week to areas where the patients had most pain. Five weeks later, one third of patients reported a significant improvement in their pain score, with very few side effects.